etanercept definition by Wordo

Noun

A

protein

drug

that

binds

to

and

blocks

the

action

of

tumor necrosis factor

and

is

administered

by

injection

to

treat

various

inflammatory

diseases

(

such

as

rheumatoid arthritis

,

psoriatic

arthritis

,

and

ankylosing spondylitis

).

It

is

a

dimeric

protein

consisting

of

the

ligand-binding

portion

of

a

human

receptor

for

tumor

necrosis

factor

linked

to

the

basal

, ,

portion

of

IgG

which

determines

the

immune

response

to

bound

antigen

.

It

is

produced

by

recombinant DNA

technology

using

hamster

ovary

cells

and

is

marketed

under

the

trademark

'''

Enbrel

'''.